The first Edition of 25 Landmark Trials in Cardiology was created in 2005-06 in response to voiced frustrations among junior medicine, cardiology and off-service residents rotating through cardiology as well as non-cardiologist physicians who were overwhelmed by the sheer number of cardiology trials. After repeated requests for references of "just the important trials" or "just the trials that changed practice", we compiled a user-friendly quick-reference guide of the 25-30 studies that had the biggest impact on clinical practice across the breadth of cardiovascular medicine. With each new addition of the resource, we continue to comb through the cardiovascular literature for robust trials that consolidate mature lines of evidence and ultimately persuade us to change practice. The unique feature of the resource is its Perspectives section that explains the study and its context. We hope this resource will be a useful and relevant companion to you.

Provides comprehensive coverage for clinicians dealing with infectious diseases. This latest update is based on the 2nd edition with additional features, enhanced functionality and ongoing updates.

5 Minute Infectious Diseases Consult, covers two major sections of chief complaints and individual diseases and disorders.

Key Features

• Comprehensive coverage of infectious diseases, important symptoms, microorganisms, and anti-infective drugs
• Coverage of emerging infectious diseases such as H1N1 flu
• Increased coverage of tropical diseases
• Updated information about management of HIV/AIDS
• 1 built-in calculator which assists in making clinical decisions
• Include summary information about individual microorganisms as well as numerous elements related to drugs for infectious disorders
• Team of international authorities provides actionable information, supported by current research and practice guidelines

A resource from the 5-Minute Consult series that focuses on neurological diseases and disorders, as well as key symptoms, signs, and tests. This latest update is based on the 2nd edition with additional features, enhanced functionality and ongoing updates.

5-Minute Neurology Consult provides instant access to comprehensive, clinically-oriented, must-have information on all disorders of the nervous system in the popular 5-Minute format.

Key Features

• Dozens of noted authorities provide tightly organized, practical guidance
• Each disease is covered in a consistent, easy-to-follow format which includes signs and symptoms, diagnosis, treatment, medications, follow-up, diseases with similar characteristics, pregnancy, synonyms, and ICD coding
• Significantly revised and expanded coverage in areas such as stroke therapy, multiple sclerosis, neurogenetic disorders, and Lewy Body dementia
• Uniform Topic organization to facilitate quick reference
• Includes 1 calculator & 1 flowchart to assist in making clinical decisions

Make the most effective diagnostic and therapeutic decisions quickly and efficiently!

Find answers fast with The 5-Minute Pediatric Consult, 8th Edition, your go-to resource for the effective medical care of infants, children, and adolescents. Using the proven 5-Minute format, it provides rapid access to information on diagnosis, treatment, medications, follow-up, and associated factors for more than 500 diseases and conditions. The 5-Minute Pediatric Consult is designed to help you make quick, accurate decisions every day helping you save time and offer every patient the best possible care.

Key Features

• Get quick access to all-new topics, including Neonatal Abstinence Syndrome, Vaccine Refusal, Zika Virus, Chikungunya Virus, Transgender Youth, and Follow-up of NICU Graduates.
• Reorganized and updated appendix includes unique identifiers for dozens of genetic conditions, associated inheritance patterns, specific gene(s) involved, mechanism of a disease, descriptions of the associated clinical findings, and a Glossary of Genetic Syndromes important for the care of children.
• Find the answers you need quickly thanks to an intuitive, at-a-glance format, with concise, bulleted text; ICD-10 codes; FAQs; and much more.
• Consult The 5-Minute Educator appendix for guidance in the clinical teaching and instruction of trainees at all levels so they can provide efficient, practical and accessible consultations in a busy clinical setting.
• Written by experts in the field of pediatrics and associated subspecialties and published by the leader in medical content

Practical and highly organized, The 5-Minute Sports Medicine Consult, 3rd Edition, is a reliable, go-to resource for clinicians in primary care, sports medicine, nursing, pediatrics, athletic training and physical therapy. This popular title provides rapid access to guidance on diagnosis, acute treatment (including on-field management), long-term treatment (including rehabilitation and referrals), and commonly asked questions for common sports-related problems seen in adult and pediatric patients. The 5-Minute Sports Medicine Consult delivers maximum clinical confidence as efficiently as possible … allowing you to focus your valuable time on giving your patients the best possible care.

KEY FEATURES

• Get quick access to all-new content , including Ankle Impingement, Femero-acetabular Impingement, Myositis Ossificans, and Vocal Cord Dysfunction
• Find the answers you need quickly thanks to an intuitive, at-a-glance format, with concise, bulleted text; return-to-play and secondary prevention information; and much more.
• Make confident decisions aided by current evidence-based designations in each topic.
• Consult useful appendices for quick answers on musculoskeletal radiography and joint and soft tissue injection.
• Written by esteemed primary care and sports medicine practitioners and published by the leading publisher in medical content

ABC of Dermatology gives a concise overview of all the essentials of dermatology for non-dermatologists. It is particularly useful in primary care, and is an excellent introduction to dermatology for nurses and medical students.

Rather than systematic description of numerous skin conditions that can overwhelm the non-specialist, a few common conditions are used as a basis for comparison with less common skin diseases. Some sections such as systemic disease and the skin, cutaneous immunology, and practical procedures are less suitable for this approach and are covered in a more didactic manner. This latest update is based on the 6th edition.

Key Features

• Fully updated with new developments and treatments, this sixth edition provides expanded coverage of psoriasis, eczema, inflammatory dermatoses and drug photosensitivity. It also includes improved coverage of the management of onychomycosis, scabies and lice, and hair and scalp, and new content on biological treatments, lymphoedema, community acquired MRSA, pityriasis rosea, immune reconstitution syndrome and antifungal drugs.
• With over 450 full color illustrations this bestselling resource ideal learning partner and resource for GPs, family physicians, junior doctors, medical students and primary care health professionals.
• Includes sections on drug rashes, connective tissue disease, skin tumors, practical procedures, laser treatments and a practical guide to dressings and bandages, this highly illustrated resources is invaluable resource for GPs, GP registrars, junior doctors, medical students and primary care nurses
• Provides a basic understanding of pathological processes which explains the characteristic features of skin diseases
• A straightforward approach to investigations and diagnoses in addition to the latest advances in the management of skin disease
• Sections cover: topical dermatology, the sun and the skin, genetics and infections, and dermatology in general practice
• Sets out the main types of clinical change that occur in and on the skin, and relates this to specific skin conditions and underlying pathological changes
• Summarizes the relevant pathological processes, diagnostic features and learning points

ABC of Diabetes, 7th Edition, provides primary care practitioners with a practical guide to all aspects of diabetes including the aetiology, diagnosis and management of Types 1 and 2 diabetes, detection and prevention, and the organization of care and support.

New to this Edition

• Advances in diabetes care take place at a rapid rate and this new edition is updated throughout to cover the latest evidence-based information for contemporary practice.
• A new chapter describes the management of severe and complex obesity complicated by diabetes and the management of patients through bariatric surgery.
• It also covers the growing number of devices and digital technology, including health informatics, that can assist in diabetes care and provides evidence of their benefit.
• With more links to useful websites and resources online, it is now easier than ever to keep up-to-date with changes.

Key Features

• A comprehensive view of the practical issues relating to diagnosis and treatment of diabetes together with very practical advice on the management of its complications
• Covers the early recognition of diabetes and cardiovascular risk as well as preventing complications specific to diabetes
• Addresses the need to deliver diabetes care in a multidisciplinary setting, including the UK Quality and Outcomes Framework, and reflects the increasing emphasis on self-management and patient-centred care, particularly as it relates to lifestyle changes, glycaemic control and patient choice over treatment options
• Contains information on retinopathy, peripheral neuropathies, autonomic neuropathy, diabetic nephropathy, cardiovascular disease, pregnancy and many more
• Sections include Insulin treatment, Hypoglycemia, Diabetic ketoacidosis and management of diabetes during pregnancy
• Gives concise and clear explanations and full-color images

This well established introduction to nutrition and special diets has been fully updated and revised.

Key Features

• Contains new charts, illustrations and guidelines on all aspects of nutrition that affect heart disease, blood pressure, and chronic diseases such as diabetes and some types of cancer.
• Contains the current nutritional recommendations for pregnancy and infant feeding as well as advice for children and adults.
• Covers nutritional deficiencies in developing and affluent countries, as well as eating disorders and obesity.
• A comprehensive guide for general practitioners, dieticians, nurses, and all junior medical staff.

Perfect for the non-specialist, Accident and Emergency Radiology focuses on common injuries and those abnormalities that are frequently overlooked or misinterpreted in the emergency department and gives key indicators when a radiologist should be consulted.

Using a concise and systematic approach, it explains how to examine and accurately interpret x-rays. Each section focuses on the basic radiographs required, important anatomy, normal variants, a system for inspecting suggested views, types of injury, and ends with a summary of key points. This latest update is based on the 3rd edition with additional features, enhanced functionality and ongoing updates!

Key Features

• Aims to provide simple and systematic approaches to the evaluation of Emergency Department radiographs.
• Valuable not only to physicians working in the Emergency Department but to others including radiologists, orthopaedic surgeons, and some pediatricians too.
• Provides greater coverage of chest radiology.
• Features more conceptual line drawings, tables, and summary charts, and improved quality of images.
• Skull section includes a comprehensive set of illustrative drawings and radiographs which can assist with the accurate assessment and interpretation of an infant's or toddler's skull films.
• Key Points summary at the end places an additional emphasis on a particularly subtle sign or appearance that is either not widely known or is regularly overlooked.
• Emphasizes pitfalls and associated abnormalities.

This international bestselling reference on acute paediatric care is the resource for the Advanced Life Support Group's Advanced Paediatric Life Support (APLS). This latest update is based on the 5th edition with additional features, enhanced functionality and ongoing updates.

Advanced Paediatric Life Support: The Practical Approach is used in emergency and paediatric departments, by physicians, nurses and allied health professionals, and its clear layout and straightforward style make it a highly practical tool both for training and in the event of an emergency. With this resource, paediatric and emergency staff can be confident in having guidance on principles and practical approaches in common situations of paediatric critical illness.

Key Features

• The latest International Liaison Committee on Resuscitation (ILCOR) 2010 Guidelines
• A discussion on the importance of human factors
• Includes 2 built-in calculators and 16 flowcharts which assist in making clinical decisions
• A new and improved design including full colour photographs and diagrams

AHA Clinical Cardiac Consult is the perfect source of fast, reliable guidance on diagnosis and management of both common and rare cardiovascular problems. This latest update is based on the 3rd edition with additional features, enhanced functionality and ongoing updates.

Key Features

• It covers more than 170 problems, diseases, syndromes, and chief complaints in the popular, easy-to-read, which includes basic information, diagnosis, treatment, medication, follow-up, ICD-9 codes and patient teaching information
• Thoroughly updated edition includes additional topics covering exercise and the heart, coronary arteries from opposite sinus, and perioperative cardiac care for noncardiac surgery along with updated references
• Additional topics including exercise and the heart, coronary arteries from the opposite sinus, and perioperative cardiac care for noncardiac surgery
• AHA input ensures accuracy
• Alphabetical order of entries provides rapid access to information

"AHFS® Drug Information™ succeeds in offering an updated drug compendium of evidence-based drug monographs, meeting the needs of today's healthcare professionals. The reference continues to be trustworthy, relying on the most prestigious and knowledgeable drug experts in the medical field.

This reference can be used by any healthcare professional utilizing or prescribing medications in their practice, including physicians, pharmacists, physician assistants, and nurse practitioners. The book is so nicely organized and easily referenced that it can also be used by students in the medical, pharmacy, and nursing fields as well." (Melissa M. Potts, BS, PharmD, Doody's Review Service, 2020)

AHFS Drug Information® 2023 - Trusted by pharmacists and other healthcare professionals for over 60 years, AHFS® DI™ is the most comprehensive evidence-based source of drug information complete with therapeutic guidelines and off-label uses.

AHFS : is the only drug information resource curated by a not-for-profit scientific organization and the only remaining original federal compendium whose authority for establishing accepted medical uses includes the broadest scope of drugs and indications under Medicaid, Medicare Part D, and more.

With expanded and revised content supported by more than 97,000 references and incorporating the advice of numerous subject matter experts, AHFS® DI™ helps you protect your patients and your practice.

2023 Updates Include:

• Drug information for COVID-19 vaccines and COVID-19 monoclonal antibodies available under FDA Emergency Use Authorizations (EUAs), including clinical considerations from the US Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), and other authorities
• Breakthroughs in oncology approved under the FDA's accelerated approval program Expanded content on off-label uses, real-world data, and long-term clinical data
• Information on patient selection and appropriate use of corticosteroids in the management of COVID-19 based on recent guidelines from NIH and the World Health Organization (WHO)
• Contemporary issues such as anticoagulant reversal strategies and use of direct oral anticoagulants versus warfarin for treatment of venous thromboembolism or atrial fibrillation
• Current best practices such as reversal of neuromuscular blocking agents for prevention of postoperative residual neuromuscular blockade
• Updated information on pharmacogenomic considerations based on recommendations from the Clinical Pharmacogenetics Implementation Consortium (CPIC)
• Additon of 51 new molecular entities (NMEs) or new therapeutic biological products approved since January 2021

Patients need up-to-date information on proper drug usage. When Patients fully understand what's expected of them, they are more likely to get the desired results from their drug therapy. FamilyRx: AHFS Patient Drug Information gives you a single source for providing important information and instructions for patients on dosing, precautions, possible side effects and interactions, and more. FamilyRx: AHFS Patient Drug Information is updated quarterly and includes home infusion and cancer chemotherapy monographs.

Family Rx: AHFS Patient Drug Information contains over 875 drug monographs and includes new and updated black box warnings. Physicians can:

• Build trust with patients by providing useful, understandable information on their medications.
• Improve communication and patient compliance.
• Empower patients to be more active and involved in their treatment.
• New and updated drug information includes:
  • Pepcid
  • Flonase
  • Paxil
  • Remicade

With FamilyRx: AHFS Patient Drug Information, positive outcomes are achieved because patients understand the benefits and potential dangers of their medications.

With Skyscape's patented smARTlink™ technology, FamilyRx™ can easily cross-index with other titles from Skyscape to provide a powerful and integrated source of clinical information that you can carry with you anytime and anywhere!

For more than 40 years ASHP has published the most trusted resource for injectable drug information. Our new ASHP® Injectable Drug InformationTM now delivers the same high-quality content that you can expect from ASHP with even MORE of the information you need to make decisive patient care decisions.

ASHP® Injectable Drug Information^TM 2023 now comes complete with 2 years of digital interactive access and a print edition to ensure you have constant, uninterrupted access. The digital content is interactive, mobile, and updated quarterly. Includes monographs to Extended Stability for Parenteral Drugs, forming a single, comprehensive resource on injectable drug information.

Backed by quality, peer-reviewed published literature and authored under the editorial authority of ASHP, it is a must-have resource for every pharmacy.

Key Features

• Quick data search for 358 drugs
• 417 monographs on parenteral drugs available in the United States and in other countries
• Monographs cross-referenced with American Society of Health-System Pharmacists (AHFS) Drug Information through AHFS classification numbers
• More than 500 revisions to existing monographs (affecting nearly 60% of the existing monographs) have been accomplished to update information on stability, compatibility, and safety (e.g., Food and Drug Administration [FDA] MedWatch alerts) and to provide more specific referencing of manufacturer information and other enhancements to the more than 24,100 compatibility pairs contained in ASHP® Injectable Drug Information™ 2023.
• How to prepare, store and administer drugs
• Information accumulated from 3,603 references
• Quick identification of drug compatibility with easy to understand icons
• Drugs listed alphabetically by generic name for efficient searching, with brand names also listed
• Tabulated results from primary research on the compatibility of the listed drug with infusion solutions and other drugs
• Four compatibility tables are provided for each drug: solution, additive, syringe, and Y-site
• Storage requirements and general stability information, including pH, freezing, exposure to light, sorption and filtration characteristics, and repackaging information
• Key product data including common sizes, strengths, volumes, and forms in which the drug is supplied. Also includes pH, osmotic value, and other important product information
• Parenteral Drugs by Caryn Bing and Anna Nowobilski-Vasilios. This extended stability information is specifically designed for use in home and other infusion practices

INFO FOR REFERENCE:

ASHP® Injectable Drug Information™ 2023 includes 18 new monographs, bringing the total in this edition to 417 monographs on parenteral drugs available in the United States and in other countries. In addition, more than 500 revisions to existing monographs (affecting nearly 60% of the existing monographs) have been accomplished to update information on stability, compatibility, and safety (e.g., Food and Drug Administration [FDA] MedWatch alerts) and to provide more specific referencing of manufacturer information and other enhancements to the more than 24,100 compatibility pairs contained in ASHP® Injectable Drug Information™ 2023. The information cited throughout the text has been compiled from 3603 references, including 195 new to this edition. Because information from pharmaceutical manufacturers had not been uniquely cited until the 18th edition, the number of unique references supporting ASHP® Injectable Drug Information™ 2023 information actually greatly exceeds this number. While primary, peer-reviewed literature remains a major source of compatibility and stability information, ongoing efforts are underway to provide increased specificity of references to the pharmaceutics research of drug manufacturers. Other relevant information and pertinent study details supplied by corresponding authors of the published literature also have been incorporated when available.

Atlas of Primary Care Procedures is a convenient how-to guide to more than 70 medical procedures most commonly performed in an office setting. Easy-to-navigate screens present step-by-step instructions for performing each procedure, plus essential information on indications, contraindications, common pitfalls, and strategies for avoiding these pitfalls. More than 295 images thoroughly demonstrate the procedures. Each entry also includes CPT code information and average fees.

Blackwell's Five-Minute Veterinary Consult: Laboratory Tests and Diagnostic Procedures: Canine & Feline is designed to provide busy veterinary practitioners and students with a complete and quick reference to diagnostic procedures and laboratory tests that are used daily in the diagnosis and management of medical problems of dogs and cats.

Each topic, written by an expert in the field, provides essential information on related physiology, indications, contraindications, potential complications, and client education. The uniform presentation of information, arranged alphabetically from abdominal radiographs to zinc tests, allows the reader to gain easy access to vital information, making this an ideal reference to be used in a clinical setting. This latest update is based on the 2009 print edition with additional features, enhanced functionality and ongoing updates!

Key Features

• Contains more than 250 procedures and tests, including blood, urine, and fecal tests and radiographic, ultrasound, and endoscopic procedures
• General information concerning appropriate test collection and principles that can be applied to major procedures such as ultrasonography, radiography, and endoscopy can be found in the front section of the resource
• The laboratory tests section of the resource enables rapid access to clinically relevant laboratory tests, with comprehensive information on test preparation, performance, factors that affect each test, and a brief guide to test interpretation.
• The diagnostic procedures section is intended to provide clinically relevant information that will enable practitioners to determine quickly whether a procedure is indicated in a particular case enough information is included to enable veterinary practitioners or technicians to perform a procedure in house.
• Other sections provide practicing veterinarians with sufficient information to understand a procedure and prepare clients and patients for a possible referral
• Appendices at the end of the resource contain tables of laboratory normal values, therapeutic drug concentrations, and a list of diagnostic laboratories

Like having a trusted clinician with you in the exam room, the fully updated Sixth Edition of Blackwell's Five-Minute Veterinary Consult: Canine and Feline continues to offer fast access to information in an easy-to-use format.

• Provides fast access to key information on the diagnosis and treatment of diseases and conditions in dogs and cats
• Covers 846 specific disorders, making it the most comprehensive quick-reference book on canine and feline medicine
• Carefully designed for fast searching and reference in the busy practice setting, giving you the confidence to make clinical decisions quickly and appropriately
• Presents contributions from 379 leading experts specializing in all areas of veterinary medicine

Written by today's leading experts, Blackwell's Five-Minute Veterinary Consult: Equine, keeps practitioners completely current with the latest in disease management of horses, taking a clear and practical approach ideal for daily equine practice. Arranged by subject for efficient searching, each topic covers clinical signs, diagnosis, treatment, and follow-up. Practitioners gain quick access to information about conditions and disorders encompassing behavior, cardiology, dermatology, endocrinology, gastroenterology, hematology, infectious diseases, laboratory tests, musculoskeletal, neonatology, neurology, ophthalmology, respiratory, theriogenology, toxicology, and urinary diseases.

Blackwell's Five-Minute Veterinary Consult: Equine, Third Edition enhances the practitioner's skills in evidence-based treatment planning, and is unmatched for its comprehensive coverage of more than 500 diseases and conditions. This handy, practical guide will help cut down on time spent navigating through other resources, so that equine veterinarians and veterinary students can study, diagnose, and treat with greater efficacy.

Key Features

• The premier all-in-one equine resource designed specifically for quick information retrieval
• Divided into identically formatted topics for easy searching by alphabetical listing or by body system
• Coverage of more than 500 diseases and conditions
• Fast access to the accumulated wisdom of hundreds of veterinary experts

Blackwell's Five-Minute Veterinary Consult Clinical Companion: Small Animal Toxicology, Second Edition puts all the information needed to rapidly and accurately manage poisonings in small animal patients at the clinician's fingertips. Using a succinct and accessible format, the book is organized by major categories of toxicants to aid in rapid differential diagnosis for suspected poisonings. All information is organized alphabetically for ease of use, while accompanying color photos aid in identification.

Key Features

• Provides concise, bulleted information focused on the most important facts needed when treating a poisoned cat or dog
• Carefully organized for ease of use in an emergency, with important toxicants arranged alphabetically within categories
• Details clinically relevant information on the most common toxicants encountered by small animals
• Presents a wealth of color photographs to aid in plant identification
• Includes 14 new topics to this edition covering cyclosporine A, sleep aids, tacrolimus, bath salts, synthetic marijuana, poisonous lizards, imidacloprid, spring bulbs, and sodium monofluoroacetate

Blackwell’s Five-Minute Veterinary Consult: Avian presents complete information on diseases and conditions seen in birds in a quick-reference format ideal for clinical practice. This new volume in the Five-Minute Veterinary Consult series offers 128 identically formatted topics on avian syndromes, written by the leading experts in the field.

Covering topics ranging from adenovirus to xanthoma, the book makes it easy to quickly find information on common conditions seen in birds. Whether avian patients are a regular or occasional part of your caseload, you’ll find this practical reference an invaluable addition to your practice library.

Key Features

• Offers fast access to essential information on 128 avian diseases and syndromes
• Written by leading experts in avian medicine
• Uses the trusted Five-Minute Veterinary Consult format
• Focuses on practical clinical knowledge

Skyscape's App is based on the print edition of Board Review Series - Pathology.

This powerful, easy-to-use resource presents the essentials of pathology in the popular Board Review Series outline format that highlights the most tested topics for the USMLE Step 1. Packed with new content; high-yield topics; concise descriptions; more than 450 USMLE-style questions with complete answers and explanations; and full-color illustrations, photomicrographs, and radiologic images, BRS Pathology, Sixth Edition, provides everything needed for course success and board exam prep.

"Try before you buy" - Download the FREE App, includes sample Chapter and 100 practice questions.

Download the App

Get it on AppStore under bundle

App Features

• Study Mode (Attempt a question, see answer and the rationale)
• Create Quiz (Select topic, number of questions - Pause and resume anytime)
• Time Mode (Answer as many questions as possible in a set time to improve your speed)
• QOD (Attempt a random question(s) every day)
• Stats (View details on topics mastered so you can focus on weak areas)
• Bookmark tricky questions and add notes - Creating flashcards

Key Features

• An easy-to-scan outline format with bolded key terms and summary tables enables concise review and exam preparation.
• Chapter-ending exams focus on high-yield, clinical content.
• An end-of-book Comprehensive Exam helps students gauge their mastery of key topics.
• New cross-references in the answers to the Comprehensive Exam use an outline format (section number/letter) to facilitate efficient study and easy linking in all formats.
• Many new full-color photomicrographsand schematic illustration provide visual learning and review.
• Key topic icons help students quickly locate important content.

Make the most informed decisions surrounding patient care with the new Braunwald's Heart Disease Practice Guidelines. Derived from the 10th edition of Braunwald's Heart Disease and offered in a convenient mobile format, this resource was designed to provide practitioners, physicians-in-training, and students at all levels with the critical tools to keep abreast of the rapidly changing scientific foundations and clinical advances in cardiovascular medicine. As new guidelines emerge, this resource will be updated by the Braunwald team of editors, who will synthesize updated information from various societies and, where appropriate, highlight important differences between guidelines.

Key Features

• Aims to broaden the knowledge base of those seeking to improve outcomes for patients afflicted with cardiovascular disease.
• Serves as a convenient resource for physicians who need high-level "take away" information to assist in patient management.
• Contains guidelines summaries for all current ACC/AHA guideline topics.
• Includes coverage of the latest guidelines on atrial fibrillation, in addition to Appropriate Use Criteria for each of the imaging modalities.