Yes for a Palm Device, most of the Skyscape references are supported on MAC.  The exceptions are: Desktop products, Smart Update.   Skyscape resources cannot be installed from a MAC to a pocket PC device, since installation requires Active Sync software and this is not supported on the MAC.  Skyscape resources cannot be installed on the MAC desktop/laptop for use on that platform.

Macintosh install instructions

Prerequisite:

• Palm Desktop installed and HotSync® working with your PDA in the cradle.

1. Download your product(s) from Skyscape updates page: http://www.skyscape.com/updates/home.asp
2. Save the <product name>.zip file to your MAC computer
3. Save the .zip file to your MAC computer. It will automatically unzip and create a folder labeled with the product name. 
4. NOTE: If you are prompted to supply a destination folder name, choose a name you are likely to remember (such as Skyscape). When the unzipping completes, files will be created in this folder (we will call this folder the Install Folder).
5. Locate the “Install Folder” and open it.
6. Add the PRC and PDB files to your Palm Install Tool.
7. If you have a memory card, then click on the button labeled change destination. Please note that only the pdb files can be loaded to the card, the prc files must remain on the main memory of the device.
8. Click on "done" in the install tool window.
9. Hotsync your device.
10. Tap Reset when prompted on device.